Estee Lauder Re-Nutriv Ultimate Youth Crème with Resveratrate

Here is the full article about sirtuins and Re-Nutriv Ultimate Youth Crème.



The ads I’ve read for Estee Lauder Re-Nutriv Ultimate Youth Crème don’t claim that it contains SIRT1, but rather that it contains a compound named Resveratrate which the company has trademarked (so we don’t know exactly what the components are).



Lauder says it is a “more potent, stable and time-released form of Resveratrol, and was shown by in vitro testing to provide six times more protection from environmental damage, more than doubling the survival rate of skin cells.”



Resveratrol is not a peptide and I haven’t seen much on its topical use. Several studies suggest that topical resveratrol has potential utility as a chemoprotective agent against skin cancer.



Resveratrol is a plant form of estrogen and when ingested acts as an antioxidant, anti-mutagen and anti-inflammatory. It is found in red wine, purple grapes, plums, peanuts and some other plants and is widely believed to reduce risk for cardiovascular disease.



A 2004 study by Howitz and Zirkin of BIOMOL International, based in Plymouth Meeting PA, demonstrated that resveratrol increases SIRT1 activity in vitro and that it significantly extends the life span of yeast and mice.



Tags: Lauder, sirtuins, SIRT1