Sirtuin Research Results - Part Two

To quote the study conducted on pro-sirtuin peptides by LMVH Recherché research lab: “facial improvements could be seen on fine lines and wrinkles, hydration, pigmented spot color intensity, complexion radiance, firmness, complexion homogeneity, and texture. Improvement in hydration was significant immediately after the first application. Skin-pixel measurement and analysis show a significant reduction of the gray variance linked to pixel heterogeneity (-4.2%) and a significant reduction of the surface of skin imperfections (-30.4%).”



The gray variance analysis is somewhat like calculating a mountain’s height from a topographical map. Wrinkles appear as darker gray pixels. Every shade of gray has a numerical value. Calculating the reduced spectrum of gray shades and the degree of discrete gray pixel lightening after treatment translate respectively into a 4.2% reduction in wrinkle depth and a 30.4% overall smoothing of the skin’s surface.



If you’re wondering why the French scientists believe these results are attributable to increased sirtuin activity specifically, that is demonstrated by the in vitro and ex vivo tests which they conducted in Petri dishes. They found “1) significantly increased SIRT1 expression in normal human dermal skin fibroblasts in vitro (+172%) and in epidermal cells of healthy human skin ex vivo and 2) decreased cell senescence and DNA fragmentation induced by ultraviolet-B (UVB) stress.”



Tags: LMVH Recherché sirtuin research, sirtuins, anti-aging peptides